There is a loader that handles switching bios'es depending on region. It was created by member zarkok and is located in the submissions thread found here. As far as the command-line for these emulators to just load the game in the cd/dvd drive, give me some time to download all these emulators and read the documentation to get the command-line for them. Also something you can try doin. Won't be able to get to this till next week though as I'm pretty busy on the weekend. Edit: ePSXe: Make sure you have the emulator working with all plugins and outside of GameEx. I don't have discs to test with but this is what I did for ePSXe. I just configured the drive in the emulator and then ran with the command-line: ePSXe.exe -nogui SSF Same rules apply. Setup the emulator (bios, cdrom drive, screen settings, etc.) and then run with the command-line below. SSF.exe Now this worked with a mounted image so it should work the same if you just want to run the emulator with the game in the drive as I'm just making my system think there is an actual disc in the drive. Come to think of it, i'm sure these can all be ported in to GameEx by importing an emulator config which is described here by Tempest, step 2. Then just tweak the command-line. Like remove [-virtualdrive-] switch since you're using actual discs or remove the daemon tools command if there's one. I haven't looked at these for some time so would have to look. Try these and then we'll move on.