Maybe with a little more details will help the situation.... again, here's what happens. I run a game (doesn't matter how, gameex, dos command, thru mameui, whatever), game starts full screen on monitor 1, after about 2 seconds appears to come out of full screen mode (very quickly), then dissappears, then cpwizard control panel shows up on monitor 2, stays for about 3 seconds then disappears, then the game comes back in full screen mode on monitor 1. hope that helps.