The issue is related to adjusting the scaling setting to 125%. I am doing this to make the icons bigger on the screens due to the high-res I am using. It also appears that this setting is enlarging the DB2S backglass images by 125% too, but this does NOT happen using PinballX.
I have it all working now by using the override DPI setting within the VP10 executable instead of the one for PinballX. So with the DPI override checked in the VP10 executable, the backglass images are shown at the normal 100% setting. Now things are consistent.
Thanks guys for chiming in.