Hi, Isn't it just the case of dropping Joytokey in the Windows Startup folder so it launches when your system is first turned on. Have you looked into possibly using Xpadder, I recently moved from JoyToKey to Xpadder and haven't looked back, plus there is a nifty little plugin made by Adultery. http://www.gameex.info/forums/topic/11376-plugin-xpadder-plugin/