If you go into advanced options GameEX (I think) offers you the option of using an external player, you could try setting up VLC or MPC to work that way, then right click on the video thats playing. I've never tried it because its not enough of a solution for my HTPC which is supposed to be mouse-less. . .but it seems like that would work. I think that this is the single most lacking feature of this otherwise very full featured and robust program. I am currently trying out front ends for my HTPC and the only thing stopping me from donating $25 and just going with gameEX instead of shopping around is the lack of ability to switch audiotracks and subtitles from within the front end. No other front end comes even close to GameEx's gaming integration. I broke a media portal install just trying to get the plugin that launches external programs working - I never even got close to using an emulator with it. Other than that its almost perfect. With ffdshow it plays most anything out of the box and I have it using coreAVC to decode full 1080p x264 video flawlessly - except that they all come on with subtitles! I stress that for me this is the only thing that makes this not really a viable option for my HTPC. . .I love it otherwise. If I get around to building my MAME cabinet I will definitely go with GameEx.