Forgive me if this has been dealt with, but I am having a heck of a time with this. I would like to be able to send sound from 2 different applications to 2 different sets of speakers running on 1 PC (using onboard and an add in sound card). To complicate things, I have Windows 7 64 bit or I would just purchase IndieVolume and be done with it. I am running the GameEx frontend so I can play MAME on my game cabinet and would like to have that sound come from my 2.1 speaker set mounted in the cabinet. I would also like to run Spotify (or a reasonable alternative) and send that sound out to my 5.1 surround sound. Seems like a reasonable request. I am tied to 4 things: 64 bit OS, MAME, streaming audio and 2 sound outputs. Anything else is negotiable. I know that Media Players such as Windows Media Player, Winamp, etc allow you to select the sound output destination and do not tie you to the default device selected in Windows. Unfortunately I cannot find a way to define this in GameEx, MAME or Spotify, If any one of those apps allowed me to choose the output my problem would be solved. I have seen an article about compiling your own MAME and incorporating a diff file but the article is from 5 years ago and doesn't reference my current setup. (forgive me if I have the details wrong here). Promising, but not quite. If there is a newer version of this topic I have been unable to find it. I have tried Fidelify, a nifty little app that does allow you to select your sound destination but requires a Premium subscription to Spotify. I have the slightly lower level Unlimited account since I do not plan to use Spotify on any mobile devices. I am not interested in paying for service I do not intend to use. I have tried different frontends for MAME (MaLa, Maximus Arcade, etc) with no luck. I have tried different streaming options (Rdio, Grooveshark) with the same results. I have tried plugins for WMP and Winamp to allow me to access streaming audio providers. No go. Pandora is nice, but I want more control over the specific songs I am going to hear. Besides, I don't know if they have a desktop app that allows you to select the output device. I have Google Music as well, but I already own those songs. I would like to hear whatever I am in the mood for and be able to access it legally. As far as I can tell web browsers use the default sound device defined in Windows which rules out several different streaming services. Virtual Audio Cable will allow me to send one sound out to multiple sets of speakers. Not what I am looking for. I know there are others out there with a similar desire to send sounds from 2 apps to 2 different sets of speakers. In fact, I'm willing to bet one of you geniuses has already done this. I have been impressed on multiple occasions at the level of knowledge on this forum. I have moderate skill level and am not afraid of tweaking, building, compiling, modifying and trying as long as I have decent instructions. If you have a solution please enlighten me so I can get back to playing Robotron . I will be forever in your debt. Thanks in advance, Cameron