Thanks for the fast advice last night. I took a look at the MAME config settings that are displayed and editable via the GameEx Setup Wizard and all appeared to be okay. Remember, previous to plugging in and configuring the X-Arcade Tankstick, my GameEx worked fine in all aspects with my MAME ROMS, launching them with no issues and running them fine with just the keyboard and mouse as user inputs. I still have the exact same problem when trying to launch a game in GameEx -- the screen changes with the controller joystick and button layout on the screen display (normal function), then the screen fades out for a couple of seconds, and then the display comes back to the GameEx screen with the "Play This Game" at the top of the menu display. No matter which game I try to launch, the same result. Argh! I disconnected the X-Arcade controller and tried running GameEx, but that did not effect the outcome which was the same. To aid in troubleshooting this time, I included 3 screen snaps from the MAME config options in GameEx. All of my MAME files are located in this root directory, "C:\Users\HoffmannFamily\Mame64". There were some folder paths that the GameEx MAME config program was looking for that I didn't have in that root, so I created a path and folders that it was looking for (default ones) just to ensure that the program wasn't hanging when trying to do something with those paths. These empty/null folders can be seen in the attached "MAME Settings4 Null Folders 7Nov.jpg" file. I hope this info helps to zero in on a simple "fix". Thanks again for the assistance here. BH